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Pregnancy education

NIPT screening

Learn when NIPT is offered, what it screens for, its benefits and limitations, and what a high-risk or inconclusive result means.

Key points

  • Ask about cost and coverage before the blood draw.

What NIPT can tell you

Noninvasive prenatal testing, or NIPT, is a blood test usually available from 10 weeks. It analyzes cell-free DNA, largely from the placenta, to estimate the chance of certain chromosome conditions, especially Down syndrome, trisomy 18, and trisomy 13. Screening and diagnostic options should be offered regardless of age. You may choose or decline testing. ACOG prenatal screening information

Benefits and limitations

NIPT is the most accurate screening approach for the common trisomies, but it does not diagnose them. The blood draw has minor risks such as bruising; it does not carry the procedure-related miscarriage risk of amniocentesis or CVS. False-positive and false-negative results can happen. How likely a positive result is to be correct depends on the condition and your circumstances.

Routine screening for rare microdeletions or broad chromosome changes is not recommended for everyone. Ask what the panel includes; more conditions on a panel do not always mean more useful answers. Twin pregnancies need specific counseling. SMFM updated guidance

What happens after a result

A high-risk result should lead to genetic counseling and an offer of diagnostic testing before making irreversible decisions. A “no result” or “low fetal fraction” result is not a normal result; it needs follow-up. Your clinician may discuss ultrasound, diagnostic testing, or a repeat blood draw based on the situation. ACOG follow-up guidance

Next step

Ask about cost and coverage before the blood draw. NIPT does not replace the anatomy scan or screening for open neural tube defects such as AFP testing.

Urgent symptoms? See when to call or go to the hospital. Emergency? Call 911.

Questions about your pregnancy? Contact Davie ObGyn in Davie, Florida, at 954-880-1010. New and established patients are welcome. This information supports your prenatal care and does not replace an individual medical assessment. For urgent symptoms, call your care team promptly; for an emergency, call 911. Do not use a routine online message for urgent symptoms.

Medically reviewed by Rahil Malik, MD, FACOG, board-certified obstetrician-gynecologist. Last reviewed: September 26, 2026. This page is general information and does not replace a visit with your doctor.

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